The Modification Strategies for Enhancing the Metabolic Stabilities and Pharmacokinetics of Aptamer Drug Candidates

Aptamers are single-stranded DNA or RNA that can mimic the functional properties of monoclonal antibodies. Aptamers have high affinity and specificity for their target molecules, which can make them a promising alternative to therapeutic antibodies or peptide ligands. However, many aptamer drug cand...

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Autores principales: Ma, Yuan, Zhang, Yihao, Chen, Zefeng, Tian, Yuan, Zhang, Ge
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2023
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Acceso en línea:https://www.intechopen.com/chapters/88030
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