Extracellular Vesicles for Therapeutic Applications

Extracellular vesicles (EVs) are cell-derived nanoparticles containing endogenous bioactivators or loading exogenously therapeutics, which serve as “messengers” in intercellular and inter-organismal communication, in both normal and pathological processes. EVs are reshaping our perspective on life s...

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Detalles Bibliográficos
Autores principales: Xu, Jianbin, Wang, Liwei, Wang, Di, Xu, Kaicheng, Chen, Liang, Yao, Minjun, Ye, Zhaoming
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2024
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Acceso en línea:https://www.intechopen.com/chapters/88820
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Descripción
Sumario:Extracellular vesicles (EVs) are cell-derived nanoparticles containing endogenous bioactivators or loading exogenously therapeutics, which serve as “messengers” in intercellular and inter-organismal communication, in both normal and pathological processes. EVs are reshaping our perspective on life science and public health. They are tools for mediating information exchange between cells and are unique in protecting and delivering their internal cargo to target cells through ligand-receptor interactions. Therefore, EVs are one of the most potential delivery systems for treating various diseases. This chapter summarizes the recent progress made in EV-based delivery systems applications, including cancer, cardiovascular diseases, liver, kidney, nervous system diseases, and COVID-19.
ISBN:978-0-85014-030-9
DOI:10.5772/intechopen.113969