Neutropenia and Hematology Analyzer

<p id="p1">The automated hematology analyzer is used to analyze white blood cell (WBC) counts. WBC differentials (WBC-diff) can be measured using a diff-scattergram. This group includes neutrophil cells. Neutrophils, characterized by their multi-lobed nuclei and a diameter ranging from 12 to 15&nbsp...

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Autor principal: Turkes, Gulsum Feyza
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2024
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Acceso en línea:https://www.intechopen.com/chapters/89047
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Sumario:<p id="p1">The automated hematology analyzer is used to analyze white blood cell (WBC) counts. WBC differentials (WBC-diff) can be measured using a diff-scattergram. This group includes neutrophil cells. Neutrophils, characterized by their multi-lobed nuclei and a diameter ranging from 12 to 15&nbsp;&mu;m, constitute about 50&ndash;70% of the leukocytes present in the bloodstream. They serve as the initial line of defense against infections in the body. Neutropenia is defined as a neutrophil count below the reference range. Neutropenia can be classified as either hematological causes or non-hematological causes. Non-hematologic causes include ethnicity, medical procedures, viral infections, autoimmune illnesses, sepsis, and congenital neutropenia. Hematological causes include myelodysplastic syndromes, acute leukemia, lymphoma, etc. The complete blood count CBC flags notify hematological analyzer operators of abnormal cell conditions, such as neutropenia. Neutropenia can manifest either independently or in conjunction with other flags. Neutropenia can be diagnosed through the utilization of peripheral blood smear tests. We can determine auto-verification rules with certain algorithms by performing a reflex test with these flags. Then, we can perform a peripheral smear analysis. The aim of this section is to explain the method that can provide early diagnosis to patients.</p>
ISBN:978-1-83634-275-5
DOI:10.5772/intechopen.114195