Dengue Virus Infection: Etiology, Epidemiology, Pathogenesis, Diagnosis, and Prevention
<p id="p1">Dengue fever, a rapidly spreading viral infection, is a global public health concern, particularly in tropical and subtropical climate-prone countries. Approximately 50% of the worldwide population is currently susceptible to acquiring the dengue virus. This study overviews the dengue vir...
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| Autores principales: | , , |
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2024
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| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/89191 |
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| Sumario: | <p id="p1">Dengue fever, a rapidly spreading viral infection, is a global public health concern, particularly in tropical and subtropical climate-prone countries. Approximately 50% of the worldwide population is currently susceptible to acquiring the dengue virus. This study overviews the dengue virus epidemiology, pathogenesis, treatment, and diagnosis. The review of 120 reports revealed 380 million dengue infections, with 100 million cases exhibiting dengue clinical characteristics resulting in thousands of annual fatalities across 129 countries. The disease’s root cause is the dengue virus transmission through the bite of an infected female mosquito, specifically the <em><italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">Aedes aegypti</italic></em> and <em><italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">Ae. albopictus</italic></em> species. The dengue virus belongs to the Flavivirus genus and Flaviviridae family. It consists of four distinct serotypes of single-stranded positive-sense RNA viruses related to their antigens. The infection can cause various disorders ranging from mild febrile illness to dengue hemorrhagic fever or shock syndrome. The diagnosis can be achieved through RT-PCR tests or testing for NS1 antigen and anti-dengue antibodies in various tissues. The incidence of dengue infections and outbreaks has significantly impacted public health in recent decades. Implementing drug standardization and population screening for early detection and treatment reduces mosquito bites and decreases death rates.</p> |
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| ISBN: | 978-0-85014-096-5 |
| DOI: | 10.5772/intechopen.114323 |