Bacterial–Viral Coinfections in Cervical Cancer

<p id="p1">Cervical cancer is a common malignancy among women, especially in the developing world. Human papillomavirus (HPV) is the necessary cause of cervical cancer, though a big proportion of women who get the infection recover without developing cervical lesions. There are certain bacterial tha...

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Detalles Bibliográficos
Autor principal: Frank, Ssedyabane
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2024
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Acceso en línea:https://www.intechopen.com/chapters/89421
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Sumario:<p id="p1">Cervical cancer is a common malignancy among women, especially in the developing world. Human papillomavirus (HPV) is the necessary cause of cervical cancer, though a big proportion of women who get the infection recover without developing cervical lesions. There are certain bacterial that have been shown to be associated with development of premalignant cervical lesions and their progression to invasive cancer. <em><italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">Chlamydia trachomatis</italic></em> (CT) and <em><italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">Treponema pallidum</italic></em> are considered potential cofactors to HPV infection and persistence; hence development of cervical cancer. The association between these coinfections and cervical lesions is thought to be based on their shared routes of transmission and the need for a breach in the continuity of the epithelium.</p>
ISBN:978-0-85014-504-5
DOI:10.5772/intechopen.115009