The Impact of HIV on Neurocognitive Performance in a Sample of Zimbabwean Children, Based on an Adapted Neurocognitive Assessment Tool

<p id="p1">Due to ongoing effects of the HIV epidemic and increasing poverty, there has been an increasing need for routine neurocognitive assessments in sub-Saharan Africa. Despite increased availability of life-saving antiretroviral drugs (ARVs), there is little attention given to the developmenta...

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Autores principales: Mlambo, Tecla, Rusakaniko, Simba, Dale, Naomi, Pullen, Sara
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2025
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Acceso en línea:https://www.intechopen.com/chapters/89603
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Sumario:<p id="p1">Due to ongoing effects of the HIV epidemic and increasing poverty, there has been an increasing need for routine neurocognitive assessments in sub-Saharan Africa. Despite increased availability of life-saving antiretroviral drugs (ARVs), there is little attention given to the developmental needs of children with HIV. The specific objectives of this study were to (1) establish if there was a significant difference between the neurocognitive performance of a sample of Zimbabwean children with versus without HIV; (2) determine which neurocognitive skills were most affected in the children with HIV; and (3) assess factors associated with poor neurocognitive performance in the sample including HIV status, gender, age, and type of school. A culturally adapted and validated tool&mdash;the Detroit Tests of Learning Aptitude (DTLA-4) was used to assess neurocognitive ability in the sample. The DTLA-4 scores of children with HIV were compared to the norms for their ages. Multivariate regression analyses determined independent predictors of children&rsquo;s neurocognitive performance and the extent to which HIV may impact their performance. Children with HIV displayed significant delay in their neurocognitive development compared to their HIV-negative peers (p &lt; .001). The implications of these findings for policy, practice, intervention and research are discussed.</p>
ISBN:978-0-85014-411-6
DOI:10.5772/intechopen.115168