<em>Cavia porcellus</em>: An Overview of Its Origin, Traditional Breeding, Selected Types for Meat Production and Biomedical Research

<p id="p1">The domestic guinea pig (<em><italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">Cavia porcellus</italic></em> Linnaeus, 1758) is a part of <em><italic xmlns:mml="http://www.w3.org/1998/Mat...

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Autores principales: Grădinaru, Andrei Cristian, Popa, Setalia
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2025
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Acceso en línea:https://www.intechopen.com/chapters/89746
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Sumario:<p id="p1">The domestic guinea pig (<em><italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">Cavia porcellus</italic></em> Linnaeus, 1758) is a part of <em><italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">Hystricomorpha</italic></em> (<em><italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">Caviomorpha</italic></em>) suborder, <em><italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">Rodentia</italic></em> order, <em><italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">Cavia</italic></em> Pallas 1766 genus. It is a rodent mammal originated from the wild ancestor <em><italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">Cavia tschudii</italic></em>, with a cosmopolitan distribution nowadays. Its breeding has some cultural-traditional arguments in its native areas, while in other parts of the world, it is used as a pet, as a source of meat, or in biomedical research. For a long time, it was a great laboratory animal and a model of research for various human pathologies. Similarities between guinea pig and human genomes were described, making possible the use of targeted knockout genes in these animals as a valuable tool for understanding gene function, modeling human diseases, and developing new therapeutic strategies. This approach provides a valuable contribution to medical research by adhering to ethical principles and seeking alternative methods for future advancements, in contrast with the concept of making guinea pigs more human-like using genetic modification, which raises ethical and practical concerns. This chapter makes an overview of the domestic guinea pig&rsquo;s origin and phylogeny, its phenotypic diversity, the process of its domestication, and the main areas of its use.</p>
ISBN:978-1-80356-392-3
DOI:10.5772/intechopen.1006117