Encapsulamiento de los aceites esenciales de citral (cymbopogon citratus) en β-ciclodextrinas usando CO2 supercrítico

By using supercritical CO2 (CO2-SC) and cyclodextrines (β-CD), it is possible to obtain complexes of inclusion (encapsulation) in the solid state with better properties of solubility, stability and bioavailability. In this study, the pressure and temperature condition were determined at which...

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Autores principales: Restrepo, Jaime, Vinasco, Luz E., Jaramillo, Lorena P., Colmenares, Ana Julia
Formato: Artículo
Lenguaje:español
Publicado: 2009
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Acceso en línea:https://dialnet.unirioja.es/servlet/oaiart?codigo=9821431
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Sumario:By using supercritical CO2 (CO2-SC) and cyclodextrines (β-CD), it is possible to obtain complexes of inclusion (encapsulation) in the solid state with better properties of solubility, stability and bioavailability. In this study, the pressure and temperature condition were determined at which the CO2 forms inclusion complexes with the aromatic oil of lemon grass (Cymbopogon Citratus) and the β-CD. The experimental design was the type 3k, with K=2 and three levels of temperature and pressure: 313.15, 323.15 and 333.15K, and 172.32, 206.78 and 241.25 bar respectively. The inclusion complexes were characterized by GC-MS,IR and UV spectroscopy comparing the spectra of β-CD, aromatic oil and the β-CD-A.E. complex. Results indicate that the highest efficiency of encapsulation (48.9%) was obtained at 241.25 bar and 313.15 K