Eosinophilic Oesophagitis: Pathophysiology, Diagnosis, and Current Management in Swallowing Disorders
<p>Eosinophilic oesophagitis (EoE) is an immune-mediated disease of the oesophagus that has become an important cause of dysphagia and food impaction in both adults and children. This chapter explains how EoE leads to epithelial injury, remodelling, and progressive narrowing of the oesophageal lumen...
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| Format: | Book Chapter |
| Language: | English |
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IntechOpen
2026
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| Online Access: | https://www.intechopen.com/chapters/1237382 |
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| _version_ | 1879164896542720000 |
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| author | Al-Hayek, Hamza Zaki, Marawan Alqudah, Eman Sadiq, Miriam |
| author_browse | Al-Hayek, Hamza Alqudah, Eman Sadiq, Miriam Zaki, Marawan |
| author_facet | Al-Hayek, Hamza Zaki, Marawan Alqudah, Eman Sadiq, Miriam |
| author_sort | Al-Hayek, Hamza |
| building | IntechOpen |
| collection | Acceso abierto |
| description | <p>Eosinophilic oesophagitis (EoE) is an immune-mediated disease of the oesophagus that has become an important cause of dysphagia and food impaction in both adults and children. This chapter explains how EoE leads to epithelial injury, remodelling, and progressive narrowing of the oesophageal lumen. It describes the most common clinical features, including intermittent dysphagia, chest discomfort, and feeding difficulties in children, along with diagnostic methods based on clinical symptoms and histological confirmation of eosinophilic infiltration. Current management options – including dietary modification, proton pump inhibitors, corticosteroid therapy, and endoscopic dilation – are reviewed. The chapter also explains the relationship between EoE and allergic or immune-related conditions, aiming to support earlier recognition, diagnosis, and more effective treatment strategies.</p> |
| doi_str_mv | 10.5772/intechopen.1014511 |
| first_indexed | 2026-10-15T21:41:37Z |
| format | Book Chapter |
| fullrecord | <oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><identifier>intech-1237382</identifier><datestamp>2026-04-15</datestamp>
<dc:title>Eosinophilic Oesophagitis: Pathophysiology, Diagnosis, and Current Management in Swallowing Disorders</dc:title>
<dc:creator>Hamza Al-Hayek</dc:creator>
<dc:creator>Marawan Zaki</dc:creator>
<dc:creator>Eman Alqudah</dc:creator>
<dc:creator>Miriam Sadiq</dc:creator>
<dc:subject>Health Sciences</dc:subject>
<dc:description><p>Eosinophilic oesophagitis (EoE) is an immune-mediated disease of the oesophagus that has become an important cause of dysphagia and food impaction in both adults and children. This chapter explains how EoE leads to epithelial injury, remodelling, and progressive narrowing of the oesophageal lumen. It describes the most common clinical features, including intermittent dysphagia, chest discomfort, and feeding difficulties in children, along with diagnostic methods based on clinical symptoms and histological confirmation of eosinophilic infiltration. Current management options &ndash; including dietary modification, proton pump inhibitors, corticosteroid therapy, and endoscopic dilation &ndash; are reviewed. The chapter also explains the relationship between EoE and allergic or immune-related conditions, aiming to support earlier recognition, diagnosis, and more effective treatment strategies.</p></dc:description>
<dc:publisher>IntechOpen</dc:publisher>
<dc:date>2026-04-15</dc:date>
<dc:type>Chapter, Part Of Book</dc:type>
<dc:identifier>https://www.intechopen.com/chapters/1237382</dc:identifier>
<dc:identifier>doi:10.5772/intechopen.1014511</dc:identifier>
<dc:language>en</dc:language>
<dc:relation>ISBN:978-1-80631-187-3</dc:relation>
<dc:rights>https://creativecommons.org/licenses/by/3.0/</dc:rights>
<dc:source>https://www.intechopen.com/books/1005265 ; Swallowing Disorders - Current Management</dc:source>
</oai_dc:dc> |
| id | intech-1237382 |
| institution | IntechOpen |
| isbn | 978-1-80631-187-3 |
| language | English |
| last_indexed | 2026-10-15T21:41:37Z |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | oai_dc |
| spelling | intech-12373822026-04-15 Eosinophilic Oesophagitis: Pathophysiology, Diagnosis, and Current Management in Swallowing Disorders Hamza Al-Hayek Marawan Zaki Eman Alqudah Miriam Sadiq Health Sciences <p>Eosinophilic oesophagitis (EoE) is an immune-mediated disease of the oesophagus that has become an important cause of dysphagia and food impaction in both adults and children. This chapter explains how EoE leads to epithelial injury, remodelling, and progressive narrowing of the oesophageal lumen. It describes the most common clinical features, including intermittent dysphagia, chest discomfort, and feeding difficulties in children, along with diagnostic methods based on clinical symptoms and histological confirmation of eosinophilic infiltration. Current management options – including dietary modification, proton pump inhibitors, corticosteroid therapy, and endoscopic dilation – are reviewed. The chapter also explains the relationship between EoE and allergic or immune-related conditions, aiming to support earlier recognition, diagnosis, and more effective treatment strategies.</p> IntechOpen 2026-04-15 Chapter, Part Of Book https://www.intechopen.com/chapters/1237382 doi:10.5772/intechopen.1014511 en ISBN:978-1-80631-187-3 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/1005265 ; Swallowing Disorders - Current Management |
| spellingShingle | Health Sciences Al-Hayek, Hamza Zaki, Marawan Alqudah, Eman Sadiq, Miriam Eosinophilic Oesophagitis: Pathophysiology, Diagnosis, and Current Management in Swallowing Disorders |
| title | Eosinophilic Oesophagitis: Pathophysiology, Diagnosis, and Current Management in Swallowing Disorders |
| title_full | Eosinophilic Oesophagitis: Pathophysiology, Diagnosis, and Current Management in Swallowing Disorders |
| title_fullStr | Eosinophilic Oesophagitis: Pathophysiology, Diagnosis, and Current Management in Swallowing Disorders |
| title_full_unstemmed | Eosinophilic Oesophagitis: Pathophysiology, Diagnosis, and Current Management in Swallowing Disorders |
| title_short | Eosinophilic Oesophagitis: Pathophysiology, Diagnosis, and Current Management in Swallowing Disorders |
| title_sort | eosinophilic oesophagitis pathophysiology diagnosis and current management in swallowing disorders |
| topic | Health Sciences |
| url | https://www.intechopen.com/chapters/1237382 |
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