Challenges for Deriving Hepatocyte-Like Cells from Umbilical Cord Mesenchymal Stem Cells for <em>In Vitro</em> Toxicology Applications

The in vitro toxicology field seeks for reliable human relevant hepatic models for predicting xenobiotics metabolism and for the safety assessment of chemicals and developing drugs. The low availability and rapid loss of the phenotype or low biotransformation activity of primary hepatocytes urged th...

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Bibliographic Details
Main Authors: Serras, Ana Sofia Martins, Cipriano, Madalena Zincke dos Reis Fernandes, Silva, Pedro Miguel da Graça, Miranda, Joana Paiva Gomes
Format: Book Chapter
Language:English
Published: IntechOpen 2020
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Online Access:https://www.intechopen.com/chapters/71523
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