Challenges for Deriving Hepatocyte-Like Cells from Umbilical Cord Mesenchymal Stem Cells for <em>In Vitro</em> Toxicology Applications

The in vitro toxicology field seeks for reliable human relevant hepatic models for predicting xenobiotics metabolism and for the safety assessment of chemicals and developing drugs. The low availability and rapid loss of the phenotype or low biotransformation activity of primary hepatocytes urged th...

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Autores principales: Serras, Ana Sofia Martins, Cipriano, Madalena Zincke dos Reis Fernandes, Silva, Pedro Miguel da Graça, Miranda, Joana Paiva Gomes
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2020
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Acceso en línea:https://www.intechopen.com/chapters/71523
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