The Application of Solid State Fermentation for Obtaining Substances Useful in Healthcare

In the current review we summarised the research involving solid state fermentation (SSF) for the production of compounds that could be used in healthcare (terpenoids, polyphenols, fibrinolytic enzymes, mycophenolic acid and others). We described several groups of obtained agents which hold various...

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Detalles Bibliográficos
Autores principales: Wajda, Łukasz, Januszek, Magdalena
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2020
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Acceso en línea:https://www.intechopen.com/chapters/73872
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Sumario:In the current review we summarised the research involving solid state fermentation (SSF) for the production of compounds that could be used in healthcare (terpenoids, polyphenols, fibrinolytic enzymes, mycophenolic acid and others). We described several groups of obtained agents which hold various activity: antimicrobial, anti-inflammatory, immunosuppressive, anticoagulant and others (e.g. anticancer or anti-diabetic). It seems that especially terpenoids and polyphenols could be useful in that field, however, other substances such as enzymes and fatty acids play important role as well. We described main groups of microorganisms that are applied in SSF of those compounds, particularly Bacillus genus and fungi, and where possible provided information regarding genes involved in those processes. We also compared various approaches toward optimisation of SSF.
ISBN:978-1-83881-180-8
DOI:10.5772/intechopen.94296