The Biological Basis of Gender Incongruence
Gender incongruence (GI) is defined as an individual’s discontent with their assigned gender at birth and their identification with a gender other than that associated with their sex based on physical sex characteristics. The origin of GI appears to be multifactorial. From the extensive research tha...
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
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IntechOpen
2022
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| Acceso en línea: | https://www.intechopen.com/chapters/80813 |
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| author | Fernández, Rosa Ramírez, Karla Delgado-Zayas, Enrique Gómez-Gil, Esther Guillamon, Antonio Pásaro, Eduardo |
| author_browse | Delgado-Zayas, Enrique Fernández, Rosa Guillamon, Antonio Gómez-Gil, Esther Pásaro, Eduardo Ramírez, Karla |
| author_facet | Fernández, Rosa Ramírez, Karla Delgado-Zayas, Enrique Gómez-Gil, Esther Guillamon, Antonio Pásaro, Eduardo |
| author_sort | Fernández, Rosa |
| building | IntechOpen |
| collection | Acceso abierto |
| description | Gender incongruence (GI) is defined as an individual’s discontent with their assigned gender at birth and their identification with a gender other than that associated with their sex based on physical sex characteristics. The origin of GI appears to be multifactorial. From the extensive research that has been conducted over the past few years, four main factors have been identified as key mechanisms: genes, hormones, epigenetics, and the environment. One of the current hypotheses suggests that GI could be related to a different sexual differentiation of the brain as a result of changes in the DNA sequence of the estrogen receptors ERs and androgen receptor AR genes. These changes in the DNA sequence would imply a variability in the sensitivity of the hormone receptors, causing a genetic vulnerability. |
| doi_str_mv | 10.5772/intechopen.103664 |
| first_indexed | 2026-10-15T21:39:42Z |
| format | Book Chapter |
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<dc:title>The Biological Basis of Gender Incongruence</dc:title>
<dc:creator>Rosa Fernández</dc:creator>
<dc:creator>Karla Ramírez</dc:creator>
<dc:creator>Enrique Delgado-Zayas</dc:creator>
<dc:creator>Esther Gómez-Gil</dc:creator>
<dc:creator>Antonio Guillamon</dc:creator>
<dc:creator>Eduardo Pásaro</dc:creator>
<dc:subject>Social Sciences and Humanities</dc:subject>
<dc:description>Gender incongruence (GI) is defined as an individual’s discontent with their assigned gender at birth and their identification with a gender other than that associated with their sex based on physical sex characteristics. The origin of GI appears to be multifactorial. From the extensive research that has been conducted over the past few years, four main factors have been identified as key mechanisms: genes, hormones, epigenetics, and the environment. One of the current hypotheses suggests that GI could be related to a different sexual differentiation of the brain as a result of changes in the DNA sequence of the estrogen receptors ERs and androgen receptor AR genes. These changes in the DNA sequence would imply a variability in the sensitivity of the hormone receptors, causing a genetic vulnerability.</dc:description>
<dc:publisher>IntechOpen</dc:publisher>
<dc:date>2022-03-15</dc:date>
<dc:type>Chapter, Part Of Book</dc:type>
<dc:identifier>https://www.intechopen.com/chapters/80813</dc:identifier>
<dc:identifier>doi:10.5772/intechopen.103664</dc:identifier>
<dc:language>en</dc:language>
<dc:relation>ISBN:978-1-80355-150-0</dc:relation>
<dc:rights>https://creativecommons.org/licenses/by/3.0/</dc:rights>
<dc:source>https://www.intechopen.com/books/11267 ; Human Sexuality</dc:source>
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| id | intech-80813 |
| institution | IntechOpen |
| isbn | 978-1-80355-150-0 |
| language | English |
| last_indexed | 2026-10-15T21:39:42Z |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | oai_dc |
| spelling | intech-808132022-03-15 The Biological Basis of Gender Incongruence Rosa Fernández Karla Ramírez Enrique Delgado-Zayas Esther Gómez-Gil Antonio Guillamon Eduardo Pásaro Social Sciences and Humanities Gender incongruence (GI) is defined as an individual’s discontent with their assigned gender at birth and their identification with a gender other than that associated with their sex based on physical sex characteristics. The origin of GI appears to be multifactorial. From the extensive research that has been conducted over the past few years, four main factors have been identified as key mechanisms: genes, hormones, epigenetics, and the environment. One of the current hypotheses suggests that GI could be related to a different sexual differentiation of the brain as a result of changes in the DNA sequence of the estrogen receptors ERs and androgen receptor AR genes. These changes in the DNA sequence would imply a variability in the sensitivity of the hormone receptors, causing a genetic vulnerability. IntechOpen 2022-03-15 Chapter, Part Of Book https://www.intechopen.com/chapters/80813 doi:10.5772/intechopen.103664 en ISBN:978-1-80355-150-0 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/11267 ; Human Sexuality |
| spellingShingle | Social Sciences and Humanities Fernández, Rosa Ramírez, Karla Delgado-Zayas, Enrique Gómez-Gil, Esther Guillamon, Antonio Pásaro, Eduardo The Biological Basis of Gender Incongruence |
| title | The Biological Basis of Gender Incongruence |
| title_full | The Biological Basis of Gender Incongruence |
| title_fullStr | The Biological Basis of Gender Incongruence |
| title_full_unstemmed | The Biological Basis of Gender Incongruence |
| title_short | The Biological Basis of Gender Incongruence |
| title_sort | biological basis of gender incongruence |
| topic | Social Sciences and Humanities |
| url | https://www.intechopen.com/chapters/80813 |
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