Novel Therapies in Clinical Development for Advanced Disease

Recent advances in melanoma treatment have supposed a dramatic transformation overcoming the situation that was faced 15 years ago, when advanced melanoma was a fatal disease, with less than five percent of patients being alive after 1 year of diagnosis. However, in spite of the impressive improveme...

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Detalles Bibliográficos
Autores principales: Arráez, Álvaro Sánchez, Maciá, Sonia, Castañón, Eduardo
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2022
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Acceso en línea:https://www.intechopen.com/chapters/83527
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Descripción
Sumario:Recent advances in melanoma treatment have supposed a dramatic transformation overcoming the situation that was faced 15 years ago, when advanced melanoma was a fatal disease, with less than five percent of patients being alive after 1 year of diagnosis. However, in spite of the impressive improvement that has been achieved with immunotherapies and targeted therapies that are completely part of the standard landscape for treatment, additional therapeutic advances are still needed. In this chapter, we review those systemic and local treatments which are undergoing clinical development, explaining their mechanisms of action and the already presented either preliminary or final results, most of them in terms of response rate.
ISBN:978-1-80356-398-5
DOI:10.5772/intechopen.107089